Iontophoresis generates an antimicrobial effect that remains after iontophoresis ceases

Effect of iontophoresis and switching iontophoresis on skin accumulation of ketoprofen.

The effect of iontophoresis and switching iontophoresis on the skin accumulation of drugs was investigated. An acrylic diffusion cell mounted with electrode cells (bore: 2.2 cm) with circular platinum electrodes (diameter: 2.0 cm) was used for the skin accumulation study. The skin accumulation of fluorescein after non-switching and switching iontophoresis was macroscopically compared with that ...

BOTOX delivery by iontophoresis.

We report two patients with severe palmar hyperhidrosis who responded to BOTOX delivered not by injection, the usual method of delivery, but by iontophoresis. The Botulinum molecule has been considered too large for delivery into the skin this way. However, other large peptides, both non-ionic and cationic, have been delivered successfully by this method, so we suspected that BOTOX could in fac...

Iontophoresis in dermatology.

Iontophoresis is the process of increasing the penetration of drugs into the skin by application of an electric current. The drug is applied under an electrode of the same charge as the drug, and a return electrode opposite in charge to the drug is placed at a neutral site on the body surface. Electrical energy assists the movement of ions across the skin using the principle "like charges repel...

Compounding for Iontophoresis

PREFACE Iontophoresis is a process which involves increased transport of solute molecules into a tissue using an electric current. This technique has been employed for the delivery of ionic drugs for local and systemic therapeutic effects in clinical settings. Iontophoresis is becoming more widespread today with many pharmacists compounding solutions for this mode of administration. Iontophores...

Ocular iontophoresis pdf